Archive for April 28th, 2009

Working the heart back into shape

April 28th, 2009

Exercise can help people recover after a heart attack but the benefits vanish when the workout stop, Swiss researchers said. Blood vessel function improved after  four weeks of exercise among people who exercized, but the findings published in the journal Circulation suggest that long-term and continuing physical activity is key to preventing another heart attack.

The Swiss team looked at 209 people who had survived a heart attack to gauge the effects of different types of exercise and what happened when people stopped regular physical activity. Volunteers were assigned to receive training in aerobic exercise , resistance workouts to build strength, or no exercise at all.

After four weeks, blood vessel function in all three exercise group improved, but there were no improvements among those who did not work out. The researchers also found that all positive benefits of working out had vanished among those in the exercise groups who stop physical activity after one month. Doctors know that exercise improves heart function after an attack but how much and what type are unclear.

Politeness

April 28th, 2009

Thank you for reading this or reading it over someone’s shoulder. Thank you for reading the previous sentence and now this sentence. Thank you!

Today, lets adopt Japanese standard of politeness. You see, there’s ordinary politeness and there’s Japanese’s politeness, a different thing altogether.

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A man was crossing the border  when a border guard told him to switch his car off. Desiderio Fortunato asked the officer to “say please”. The guard repeated his order. The motorist repeated his request. The officer blinded the motorist with pepper spray, dragged him out of his car, hancuffed him and detained him for three hours.

Compare Japan. In that country, everyone spends so much time saying “please” and “thank you” that it makes several hours to exchange even the tiniest bit of information such as: “You are standing on my foot.”  And you don’t just use words. You bow. The more polite you are, the lower you bow. Losing your balance and collapsing onto your boss’s wife’s knees is quite common and is considered an extremely polite thing to do.

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Take a ride on the Gomen Nahari Line, a railway in Kochi Prefecture and you’ll find one station is called “Arigato”, which means “thank you”, and another is “Gomen”, which means “sorry.” Turning the pair into Thank You Station and Sorry Station was the idea of Takashi Yanase. Mr. Takashi is famed for his original thinking, being the creator of the cartoon superhero Anpanman, a bean paste-filled roll of bread which fights crime with superhuman (super bakery items…) powers.

The obvious question, at least to anyone non-Japanese, is: Why? Why do they have those names? What is Thank You Station thankful for, and what is Sorry Station apologizing for? There’s no answer to this. Polite terms do not need a reason to be uttered. Just saying “sorry” and “thank you” together makes you feel good. The Japanese, like British, scatter polite terms around like confeti to create a general feeling of positivity. Summit meetings between Japanese and British delegations often run out of time before the first item on the agenda, because of the sheer scale of pleasantries involved.

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A U.S. sports reporter attended a Tokyo baseball match. At the end of the games, the players bow toward the field, and even the losing team. But you can take the whole politeness thing too far. In Japan, people have bowed on railway platforms and had their heads hit by trains. There have been cases where two individuals have met and bowed simultaneously, knocking each other out. Escalators in Japan are really dangerous places. People going down recognize someone going up and they bow, losing their balance and causing fatal accidents. But no one complains about it. That would not be polite.

Thank you for reading this.

thanks

New insights to fighting colds

April 28th, 2009
flu

achoo!

Researchers who mapped the DNA of more than 100 different cold viruses said recently they have discovered a shortcut in their life cycle, which may explain why they can inflict misery so quickly. They also believe they may be able to design drugs to fight the rhinoviruses, which use their single gene to move rapidly from person to person, causing symptoms that range from irritating sniffles to pneumonia.

Instead of designing one drug to cure the common cold, several may be needed because the virus mutates so efficiently. The hope had been that it might be easy to fight the viruses, which sicken children on average 10 times a year and adults at least twice a year on average.

This is because any rhinovirus has just one gene, which in turn makes a giant protein that appears to do little or nothing until it gets chopped up into 11 smaller pieces by an enzyme called a protease. Researchers tried to attack this big, clumsy protein before it gets chopped up.

The first drug, the virus mutated around it. But now the researchers said now they have all the pieces, they will begin to understand what areas are not so flexible then will begin to do some more rational drug design. For example, it might be possible to attack the protease – an approach that has worked in fighting AIDS.

If the researchers could inhibit the protease from cleaving that protein, maybe they could render all rhinoviruses ineffective.